CPLX1 Antibody

• Background:

  CPLX1 encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release.

• NCBI Gene ID:

  10815

• Swiss Prot:

  O14810

• Accession Number:

  O14810

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This CPLX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-60 amino acids from the Central region of human CPLX1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  15 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CPLX1

• NCBI Official Name:

  Complexin-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Salimi, K., et al. Synapse 62 (4) :273-282 (2008)

• Background Reference 02:

  Giraudo, C.G., et al. Science 313 (5787) :676-680 (2006)

• Background Reference 03:

  Kishi, T., et al. Schizophr. Res. 82 (2-3), 185-189 (2006) :

• Background Reference 04:

  Basso, M., et al. Proteomics 4 (12) :3943-3952 (2004)

• Other Product Names:

  Complexin-1, Complexin I, CPX I, Synaphin-2, CPLX1

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid