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CPLX1 Antibody

CAT: 0223-63-934Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-934Size:400 µL
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Background
CPLX1 encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release.
NCBI Gene ID
10815
Swiss Prot
O14810
Accession Number
O14810
Host
Rabbit
Reactivity
Mouse
Immunogen
This CPLX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-60 amino acids from the Central region of human CPLX1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
15 kDa
Fragment
Rabbit Ig
Symbol
CPLX1
NCBI Official Name
Complexin-1
NCBI Organism
Homo sapiens
Background Reference 01
Salimi, K., et al. Synapse 62 (4) :273-282 (2008)
Background Reference 02
Giraudo, C.G., et al. Science 313 (5787) :676-680 (2006)
Background Reference 03
Kishi, T., et al. Schizophr. Res. 82 (2-3), 185-189 (2006) :
Background Reference 04
Basso, M., et al. Proteomics 4 (12) :3943-3952 (2004)
Other Product Names
Complexin-1, Complexin I, CPX I, Synaphin-2, CPLX1
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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