CROT Antibody

CAT: 0223-63-919Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-63-919Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CROT encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
NCBI Gene ID
54677
Swiss Prot
Q9UKG9
Accession Number
Q9UKG9
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CROT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-79 amino acids from the N-terminal region of human CROT.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
70 kDa
Fragment
Rabbit Ig
Symbol
CROT
NCBI Official Name
Peroxisomal carnitine O-octanoyltransferase
NCBI Organism
Homo sapiens
Background Reference 01
Li, Y.L., et al. FEBS J. 276 (1) :303-314 (2009)
Background Reference 02
Morillas, M., et al. J. Biol. Chem. 277 (13) :11473-11480 (2002)
Background Reference 03
Van der Leij, F.R., et al. Mol. Genet. Metab. 71 (1-2), 139-153 (2000) :
Background Reference 04
Ferdinandusse, S., et al. Biochem. Biophys. Res. Commun. 263 (1) :213-218 (1999)
Other Product Names
Peroxisomal carnitine O-octanoyltransferase, COT, CROT, COT
Tested Applications
WB, IHC-P, Flow
Protein ID
48429265
Physical Properties
Liquid

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