TCHP Antibody

• Background:

  TCHP may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. This protein may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.

• NCBI Gene ID:

  84260

• Swiss Prot:

  Q9BT92

• Accession Number:

  Q9BT92

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This TCHP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-320 amino acids from the Central region of human TCHP.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  61 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  TCHP

• NCBI Official Name:

  Trichoplein keratin filament-binding protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Vecchione, A. Oncogene 28 (2), 257-269 (2009)

• Background Reference 02:

  Tokumasu, F. J. Cell. Sci. 118 (PT 5), 1091-1098 (2005)

• Background Reference 03:

  Nishizawa, M. J. Cell. Sci. 118 (PT 5), 1081-1090 (2005)

• Other Product Names:

  Trichoplein keratin filament-binding protein, Protein TCHP, Mitochondrial protein with oncostatic activity, Mitostatin, Tumor suppressor protein, TCHP {ECO:0000312|EMBL:AAH042851}

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  74733103

• Physical Properties:

  Liquid