TCHP Antibody

• Background :

  TCHP may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. This protein may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.

• NCBI Gene ID :

  84260

• Swiss Prot :

  Q9BT92

• Accession Number :

  Q9BT92

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This TCHP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-320 amino acids from the Central region of human TCHP.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  61 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  TCHP

• NCBI Official Name :

  Trichoplein keratin filament-binding protein

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Vecchione, A. Oncogene 28 (2), 257-269 (2009)

• Background Reference 02 :

  Tokumasu, F. J. Cell. Sci. 118 (PT 5), 1091-1098 (2005)

• Background Reference 03 :

  Nishizawa, M. J. Cell. Sci. 118 (PT 5), 1081-1090 (2005)

• Other Product Names :

  Trichoplein keratin filament-binding protein, Protein TCHP, Mitochondrial protein with oncostatic activity, Mitostatin, Tumor suppressor protein, TCHP {ECO:0000312|EMBL:AAH042851}

• Tested Applications :

  WB, IHC-P, Flow

• Protein ID :

  74733103

• Physical Properties :

  Liquid