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GUSB Antibody

CAT: 0223-63-905Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-905Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The GUSB gene encodes beta-glucuronidase (EC 3.2.1.31), a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans (Shipley et al., 1993 [PubMed 7680524]) . It is a tetrameric glycoprotein composed of identical subunits (Oshima et al., 1987 [PubMed 3468507]) . The GUSB gene is mutated in mucopolysaccharidosis type VII (MPS7; MIM 253220) .
NCBI Gene ID
2990
Swiss Prot
P08236
Accession Number
P08236
Host
Rabbit
Reactivity
Human
Immunogen
This GUSB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 335-362 amino acids from the Central region of human GUSB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Pig
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
75 kDa
Fragment
Rabbit Ig
Symbol
GUSB
NCBI Official Name
Beta-glucuronidase
NCBI Organism
Homo sapiens
Background Reference 01
Tomatsu, S. Hum. Mutat. 30 (4), 511-519 (2009)
Background Reference 02
Romanowski, T. Med. Sci. Monit. 14 (7), BR147-BR152 (2008)
Background Reference 03
Gratz, M. Pharmacogenet. Genomics 15 (12), 875-881 (2005)
Other Product Names
Beta-glucuronidase, Beta-G1, GUSB
Tested Applications
WB, IHC-P, Flow
Protein ID
146345377
Physical Properties
Liquid

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