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VGFR1 Antibody

CAT: 0223-63-888Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-888Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
VGFR1 encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig) -like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes.
NCBI Gene ID
2321
Swiss Prot
P17948
Accession Number
P17948
Host
Rabbit
Reactivity
Human
Immunogen
This VGFR1 antibody is generated from rabbits immunized with human VGFR1 recombinant protein.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
151 kDa
Fragment
Rabbit Ig
Symbol
FLT1
NCBI Official Name
Vascular endothelial growth factor receptor 1
NCBI Organism
Homo sapiens
Background Reference 01
Srinivas, S.K., et.al., Am. J. Obstet. Gynecol. 202 (5), 445 (2010)
Background Reference 02
Gomez, L.M., et.al., Am. J. Obstet. Gynecol. 202 (4), 386 (2010)
Background Reference 03
Al-Ani, B., et.al., Hypertension 55 (3), 689-697 (2010)
Background Reference 04
Wong, N.S., et.al., J. Clin. Oncol. 28 (5), 723-730 (2010)
Other Product Names
Vascular endothelial growth factor receptor 1, VEGFR-1, Fms-like tyrosine kinase 1, FLT-1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, FLT, Vascular permeability factor receptor, FLT1, FLT, FRT, VEGFR1
Tested Applications
WB, IHC-P, Flow
Protein ID
143811474
Physical Properties
Liquid

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