GABRD Antibody

• Background:

  GABRD is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This protein encodes the delta subunit.

• NCBI Gene ID:

  2563

• Swiss Prot:

  O14764

• Accession Number:

  O14764

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GABRD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-358 amino acids from the Central region of human GABRD.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  51 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  GABRD

• NCBI Official Name:

  Gamma-aminobutyric acid receptor subunit delta

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Gratacos, M., et.al., Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (6), 808-816 (2009)

• Background Reference 02:

  Maldonado-Aviles, J.G., et.al., AmPsychiatry 166 (4), 450-459 (2009)

• Background Reference 03:

  Tabakoff, B., et.al., BMC Biol. 7, 70 (2009)

• Other Product Names:

  Gamma-aminobutyric acid receptor subunit delta, GABA (A) receptor subunit delta, GABRD

• Tested Applications:

  WB, IHC-P, Flow

• Physical Properties:

  Liquid