EFEMP2 Antibody

• Background:

  EFEMP2 have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The protein contains four EGF2 domains and six calcium-binding EGF2 domains. This protein is necessary for elastic fiber formation and connective tissue development.

• NCBI Gene ID:

  30008

• Swiss Prot:

  O95967

• Accession Number:

  O95967

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This EFEMP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-414 amino acids from the C-terminal region of human EFEMP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Hamster

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  49 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  EFEMP2

• NCBI Official Name:

  EGF-containing fibulin-like extracellular matrix protein 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Chen, Q., et.al., Biochem. J. 423 (1), 79-89 (2009)

• Background Reference 02:

  Choudhury, R., et.al., J. Biol. Chem. 284 (36), 24553-24567 (2009)

• Background Reference 03:

  El-Hallous, E., et.al., J. Biol. Chem. 282 (12), 8935-8946 (2007)

• Other Product Names:

  EGF-containing fibulin-like extracellular matrix protein 2, Fibulin-4, FIBL-4, Protein UPH1, EFEMP2, FBLN4

• Tested Applications:

  WB, Flow

• Physical Properties:

  Liquid