PEX14 Antibody

• Background:

  PEX14 belongs to the peroxin 14 family. It is a component of the peroxisomal translocation machinery with PEX13 and PEX17 and interacts with both the PTS1 and PTS2 receptors. PEX14 binds directly to PEX17. Defects in PEX14 are the cause of peroxisome biogenesis disorder complementation group K (PBD-CGK) [MIM:601791] and Zellweger syndrome (ZWS) [MIM:214100].

• NCBI Gene ID:

  5195

• Swiss Prot:

  O75381

• Accession Number:

  O75381

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PEX14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-370 amino acids from the C-terminal region of human PEX14.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  41 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PEX14

• NCBI Official Name:

  Peroxisomal membrane protein PEX14

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Neufeld C., et.al., EMBO J. 28:745-754 (2009) .

• Other Product Names:

  Peroxisomal membrane protein PEX14, PTS1 receptor-docking protein, Peroxin-14, Peroxisomal membrane anchor protein PEX14, PEX14

• Tested Applications:

  WB, IHC-P, Flow

• Physical Properties:

  Liquid