PEX1 Antibody

• Background :

  This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome.

• NCBI Gene ID :

  5189

• Swiss Prot :

  O43933

• Accession Number :

  O43933

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This PEX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 599-628 amino acids from the Central region of human PEX1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  143 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  PEX1

• NCBI Official Name :

  Peroxisome biogenesis factor 1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :

• Background Reference 02 :

  Yik, W.Y., et al. Hum. Mutat. 30 (3), E467-E480 (2009) :

• Background Reference 03 :

  Gudbjartsson, D.F., et al. Nat. Genet. 40 (5) :609-615 (2008)

• Background Reference 04 :

  Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

• Other Product Names :

  Peroxisome biogenesis factor 1, Peroxin-1, Peroxisome biogenesis disorder protein 1, PEX1

• Tested Applications :

  WB

• Physical Properties :

  Liquid