PEX12 Antibody

CAT: 0223-64-021Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-64-021Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle.
NCBI Gene ID
5193
Swiss Prot
O00623
Accession Number
O00623
Host
Rabbit
Reactivity
Human
Immunogen
This PEX12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-158 amino acids from the Central region of human PEX12.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PEX12
NCBI Official Name
Peroxisome assembly protein 12
NCBI Organism
Homo sapiens
Background Reference 01
Zeharia, A., et al. J. Hum. Genet. 52 (7) :599-606 (2007)
Background Reference 02
Mano, S., et al. Plant J. 47 (4) :604-618 (2006)
Background Reference 03
Gootjes, J., et al. Hum. Mutat. 24 (2) :130-139 (2004)
Other Product Names
Peroxisome assembly protein 12, Peroxin-12, Peroxisome assembly factor 3, PAF-3, PEX12, PAF3
Tested Applications
WB
Physical Properties
Liquid

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