NUP153 Antibody

• Background:

  Nuclear pore complexes are extremely elaborate structures that mediate the regulated movement of macromolecules between the nucleus and cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are pore complex-specific glycoproteins characterized by cytoplasmically oriented O-linked N-acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. This protein has three distinct domains: a N-terminal region within which a pore targeting domain has been identified, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats.

• NCBI Gene ID:

  9972

• Swiss Prot:

  P49790

• Accession Number:

  P49790

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NUP153 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the N-terminal region of human NUP153.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  154 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  NUP153

• NCBI Official Name:

  Nuclear pore complex protein Nup153

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Olsen, J.V., et.al., Cell 127 (3), 635-648 (2006)

• Background Reference 02:

  Ullman, K.S., et.al., Mol. Biol. Cell 10 (3), 649-664 (1999)

• Other Product Names:

  Nuclear pore complex protein Nup153, 153 kDa nucleoporin, Nucleoporin Nup153, NUP153

• Tested Applications:

  WB, Flow

• Protein ID:

  206729891

• Physical Properties:

  Liquid