CDIPT Antibody

• Background:

  CDIPT is a protein which is phosphatidylinositol breakdown products that are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. Two enzymes, CDP-diacylglycerol synthase and phosphatidylinositol synthase, are involved in the biosynthesis of phosphatidylinositol. Phosphatidylinositol synthase, a member of the CDP-alcohol phosphatidyl transferase class-I family, is an integral membrane protein found on the cytoplasmic side of the endoplasmic reticulum and the Golgi apparatus.

• NCBI Gene ID:

  10423

• Swiss Prot:

  O14735

• Accession Number:

  O14735

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This CDIPT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-125 amino acids from the Central region of human CDIPT.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  24 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CDIPT

• NCBI Official Name:

  CDP-diacylglycerol--inositol 3-phosphatidyltransferase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  De Serres, F.J., et.al., Monaldi Arch Chest Dis 63 (3), 133-141 (2005)

• Background Reference 02:

  Lykidis, A., et.al., J. Biol. Chem. 272 (52), 33402-33409 (1997)

• Other Product Names:

  CDP-diacylglycerol--inositol 3-phosphatidyltransferase, Phosphatidylinositol synthase, PI synthase, PtdIns synthase, CDIPT, PIS, PIS1

• Tested Applications:

  WB, IHC-P, Flow

• Physical Properties:

  Liquid