JIP1 Antibody

• Background:

  JIP1 is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8) . This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2.

• NCBI Gene ID:

  9479

• Swiss Prot:

  Q9UQF2

• Accession Number:

  Q9UQF2

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This JIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 470-498 amino acids from the C-terminal region of human JIP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  78 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  MAPK8IP1

• NCBI Official Name:

  C-Jun-amino-terminal kinase-interacting protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Mooser, V., et.al., Genomics 55 (2), 202-208 (1999)

• Other Product Names:

  C-Jun-amino-terminal kinase-interacting protein 1, JIP-1, JNK-interacting protein 1, Islet-brain 1, IB-1, JNK MAP kinase scaffold protein 1, Mitogen-activated protein kinase 8-interacting protein 1, MAPK8IP1, IB1, JIP1, PRKM8IP

• Tested Applications:

  WB, IHC-P, IF, Flow

• Protein ID:

  17433093

• Physical Properties:

  Liquid