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UNC13B Antibody

CAT: 0223-63-695Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-63-695Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
UNC13B plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP) . It is essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity) .
NCBI Gene ID
10497
Swiss Prot
O14795
Accession Number
O14795
Host
Rabbit
Reactivity
Human
Immunogen
This UNC13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1062-1091 amino acids from the Central region of human UNC13B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
181 kDa
Fragment
Rabbit Ig
Symbol
UNC13B
NCBI Official Name
Protein unc-13 homolog B
NCBI Organism
Homo sapiens
Background Reference 01
Sjoeblom T., et.al., Science 314:268-274 (2006) .
Background Reference 02
Yu L.-R., Zhu Z., et.al., J. Proteome Res. 6:4150-4162 (2007) .
Other Product Names
Protein unc-13 homolog B, Munc13-2, munc13, UNC13B, UNC13
Tested Applications
WB, Flow
Physical Properties
Liquid

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