CTPS2 Antibody

• Background:

  CTPS2 catalyzes the formation of CTP from UTP with the concomitant eamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy.

• NCBI Gene ID:

  56474

• Swiss Prot:

  Q9NRF8

• Accession Number:

  Q9NRF8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CTPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-105 amino acids from the N-terminal region of human CTPS2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  66 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CTPS2

• NCBI Official Name:

  CTP synthase 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Olsen, J.V., et.al., Cell 127 (3), 635-648 (2006)

• Other Product Names:

  CTP synthase 2, CTP synthetase 2, UTP--ammonia ligase 2, CTPS2

• Tested Applications:

  WB, Flow

• Protein ID:

  74752919

• Physical Properties:

  Liquid