HSPA6 Antibody

• Background:

  In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.

• NCBI Gene ID:

  3310

• Swiss Prot:

  P17066

• Accession Number:

  P17066

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This HSPA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 544-571 amino acids from the C-terminal region of human HSPA6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  71 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  HSPA6

• NCBI Official Name:

  Heat shock 70 kDa protein 6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Leung, T.K., et.al., Genomics 12 (1), 74-79 (1992)

• Other Product Names:

  Heat shock 70 kDa protein 6, Heat shock 70 kDa protein B', HSPA6, HSP70B'

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  34978357

• Physical Properties:

  Liquid