HSPA4 Antibody

CAT: 0223-26-101Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-26-101Size:100 µL
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Background
HSPA4 (Hsp70) belongs to the heat shock protein 70 family. It was isolated as a putative Rictor interacting protein and interaction with membranes acts as a platform for its release into the extracellular environment during its recovery from stress. Hsp70 gene expression in Rheumatoid Arthitis-affected synovial tissue is followed by Hsp70 cell surface expression on fibroblast-like synovial cells growing from RA synovial tissue. Serum Hsp70 levels were increased in Systemic sclerosis patients, and associated with pulmonary fibrosis, skin sclerosis, renal vascular damage, oxidative stress, and inflammation.
NCBI Gene ID
3308
Swiss Prot
P34932
Accession Number
NP_002145
Host
Rabbit
Reactivity
Human, Mouse, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HSPA4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HSPA4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
94 kDa
Applications Notes
HSPA4 antibody can be used for detection of HSPA4 by ELISA at 1:62500. HSPA4 antibody can be used for detection of HSPA4 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
HSPA4
NCBI Official Name
Heat shock 70kDa protein 4
NCBI Organism
Homo sapiens
Background Reference 01
Kim, H.E., (2008) Mol. Cell 30 (2), 239-247.
Other Product Names
HSPA4, APG-2, HS24/P52, MGC131852, RY, hsp70, hsp70RY, HSPH2, HEL-S-5a
Tested Applications
ELISA, WB
Protein ID
38327039
Physical Properties
Liquid

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