CNTNAP2 Antibody

• Background:

  CNTNAP2 is a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C omain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons.

• NCBI Gene ID:

  26047

• Swiss Prot:

  Q9UHC6

• Accession Number:

  Q9UHC6

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CNTNAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1079-1106 amino acids from the Central region of human CNTNAP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  148 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CNTNAP2

• NCBI Official Name:

  Contactin-associated protein-like 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Denisenko-Nehrbass, N., et.al., Eur. J. Neurosci. 17 (2), 411-416 (2003)

• Background Reference 02:

  Nakayama, M., et.al., Genome Res. 12 (11), 1773-1784 (2002)

• Other Product Names:

  Contactin-associated protein-like 2, Cell recognition molecule Caspr2, CNTNAP2, CASPR2 {ECO:0000303|PubMed:10624965}, KIAA0868

• Tested Applications:

  WB, IHC-P

• Protein ID:

  17433089

• Physical Properties:

  Liquid