MOSC2 Antibody

• Background:

  Catalytic component of the benzamidoxime prodrug-converting complex, a complex required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. Benzamidoxime is an amidine prodrug produced by N-hydroxylation which is used to enhance bioavailability and increase intestinal absorption. It is then reduced into benzamidine, its active amidine, by the benzamidoxime prodrug-converting complex.

• NCBI Gene ID:

  54996

• Swiss Prot:

  Q969Z3

• Accession Number:

  Q969Z3

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MOSC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-300 amino acids from the C-terminal region of human MOSC2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  38 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  MARCH2

• NCBI Official Name:

  Mitochondrial amidoxime reducing component 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Havemeyer, A., et.al., J. Biol. Chem. 281 (46), 34796-34802 (2006)

• Background Reference 02:

  Simpson, J.C., et.al., EMBO Rep. (3), 287-292 (2000)

• Other Product Names:

  Mitochondrial amidoxime reducing component 2, mARC2, 1---, Molybdenum cofactor sulfurase C-terminal domain-containing protein 2, MOSC domain-containing protein 2, Moco sulfurase C-terminal domain-containing protein 2, MARC2, MOSC2

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  74760692

• Physical Properties:

  Liquid