RegisterLogin

HK2 Antibody

CAT: 0223-63-421Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-63-421Size:400 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase activity is involved in the first step in several metabolic pathways. HK3 is bound to the outer mitochondrial membrane. Its hydrophobic N-terminal sequence may be involved in membrane bindng. It is the predominant hexokinase isozyme expressed in insuline-responsive tissues such as skeletal muscle. The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated wiht the N-terminus. Although found in NIDDM patients, genetic variations of HK2 do not contribute to the disease.
NCBI Gene ID
3099
Swiss Prot
P52789
Accession Number
P52789
Host
Rabbit
Reactivity
Human
Immunogen
This HK2 (Hexokinase II) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-121 amino acids from the N-terminal region of human HK2 (Hexokinase II) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
102 kDa
Fragment
Rabbit Ig
Symbol
HK2
NCBI Official Name
Hexokinase-2
NCBI Organism
Homo sapiens
Background Reference 01
Lehto, M., et al., Diabetologia 38 (12) :1466-1474 (1995) .
Background Reference 02
Vidal-Puig, A., et al., Diabetes 44 (3) :340-346 (1995) .
Background Reference 03
Laakso, M., et al., Diabetes 44 (3) :330-334 (1995) .
Background Reference 04
Echwald, S.M., et al., Diabetes 44 (3) :347-353 (1995) .
Other Product Names
Hexokinase-2, Hexokinase type II, HK II, Muscle form hexokinase, HK2
Tested Applications
WB, IHC-P
Protein ID
56405344
Physical Properties
Liquid

Related Products

CatalogName
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
XG-6108Fibrinogen Antibody
XG-6110Galactosidase Antibody
XG-6122PKNOX11 Antibody
XG-6124Leptin Antibody
XG-6125Leptin Antibody
XG-6126Leptin Antibody
XG-6127ALBP Antibody

Alternative Products

CatalogName
E19-2911-2CD11b Antibody Antibody
E36403ZNF98 Antibody Antibody
MBS8529199-01H2B Antibody Antibody
MBS850197-01Antibody to IGFBP2 Antibody
DF8746-01ASAP1 antibody Antibody
MBS9403836-01SZT2 Antibody Antibody
E8M1007-4HSP60 Antibody Antibody
GWB-250026Lck antibody Antibody
LSMab09882anti-Antibody^Polyclonal antibody control antibody
MBS850537-01Antibody Pair to APOA5 Antibody

Popular Products