AK2 Antibody

• Background :

  Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis.

• NCBI Gene ID :

  204

• Swiss Prot :

  P54819

• Accession Number :

  P54819

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This AK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-217 amino acids from the C-terminal region of human AK2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Obesity, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  26 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  AK2

• NCBI Official Name :

  Adenylate kinase 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03168}

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Noma, T., et al., Biochim. Biophys. Acta 1395 (1) :34-39 (1998) .

• Background Reference 02 :

  Lee, Y., et al., J. Biochem. 123 (1) :47-54 (1998) .

• Background Reference 03 :

  Lee, Y., et al., Biochem. Mol. Biol. Int. 39 (4) :833-842 (1996) .

• Background Reference 04 :

  Bruns, G.A., et al., Biochem. Genet. 15 (5-6), 477-486 (1977) .

• Other Product Names :

  Adenylate kinase 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03168}, AK 2 {ECO:0000255|HAMAP-Rule:MF_03168}, 2743 {ECO:0000255|HAMAP-Rule:MF_03168}, ATP-AMP transphosphorylase 2 {ECO:0000255|HAMAP-Rule:MF_03168}, ATP:AMP phosphotransferase {ECO:0000255|HAMAP-Rule:MF_03168}, Adenylate monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03168}, Adenylate kinase 2, mitochondrial, N-terminally processed {ECO:0000255|HAMAP-Rule:MF_03168}, AK2 {ECO:0000255|HAMAP-Rule:MF_03168}, ADK2

• Tested Applications :

  WB, IHC-P

• Protein ID :

  1708596

• Physical Properties :

  Liquid