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DGKA Antibody

CAT: 0223-63-409Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-409Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Upon cell stimulation, the kinase DGKA converts the second messenger diacylglycerol into phophatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity. DGKA is stimulated by calcium and phosphatidylserine, and is phosphorylated by protein kinase C. Tissue expression is in lymphocytes and oligodengroglial cells. DGKA contains 2 zinc-dependent phorbol-ester and DAG binding domains, and 2 EF-hand calcium binding domains.
NCBI Gene ID
1606
Swiss Prot
P23743
Accession Number
P23743
Host
Rabbit
Reactivity
Human
Immunogen
This DGKA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 598-628 amino acids from the C-terminal region of human DGKA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
83 kDa
Fragment
Rabbit Ig
Symbol
DGKA
NCBI Official Name
Diacylglycerol kinase alpha
NCBI Organism
Homo sapiens
Background Reference 01
Hart, T.C., et al., Genomics 22 (1) :246-247 (1994) .
Background Reference 02
Hart, T.C., et al., Mamm. Genome 5 (2) :123-124 (1994) .
Background Reference 03
Schaap, D., et al., FEBS Lett. 275 (1-2), 151-158 (1990) .
Other Product Names
Diacylglycerol kinase alpha, DAG kinase alpha, 80 kDa diacylglycerol kinase, Diglyceride kinase alpha, DGK-alpha, DGKA, DAGK, DAGK1
Tested Applications
WB, IHC-P
Protein ID
281185505
Physical Properties
Liquid

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