DGKB Antibody

• Background :

  Diacylglycerol (DAG) is an allosteric activator of protein kinase C. DAG also participates in regulating RAS and RHO family proteins by activating the guanine nucleotide exchange factors VAV and RASGRP1. DAG is also involved in the synthesis of phospholipids and triacylglycerols. Tight regulation of DAG levels is achieved via DAG kinases (DGKs), which remove DAG by phosphorylate it to phosphatidic acid. Several mammalian isozymes of DAGK have been identified

• NCBI Gene ID :

  1607

• Swiss Prot :

  Q9Y6T7

• Accession Number :

  Q9Y6T7

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This DGKB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 773-804 amino acids from the C-terminal region of human DGKB.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Obesity, Signal Transduction

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  91 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  DGKB

• NCBI Official Name :

  Diacylglycerol kinase beta

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Caricasole, A., et al., J. Biol. Chem. 277 (7) :4790-4796 (2002) .

• Other Product Names :

  Diacylglycerol kinase beta, DAG kinase beta, 90 kDa diacylglycerol kinase, Diglyceride kinase beta, DGK-beta, DGKB, DAGK2, KIAA0718

• Tested Applications :

  WB, IHC-P

• Protein ID :

  12643960

• Physical Properties :

  Liquid