PRPK Antibody

CAT: 0223-63-395Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-63-395Size:400 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K) . MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
NCBI Gene ID
112858
Swiss Prot
Q96S44
Accession Number
Q96S44
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This PRPK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-249 amino acids from the Central region of human PRPK.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Symbol
TP53RK
NCBI Official Name
TP53-regulating kinase
NCBI Organism
Homo sapiens
Background Reference 01
Miyoshi, A., et al., Biochem. Biophys. Res. Commun. 303 (2) :399-405 (2003) .
Background Reference 02
Abe, Y., et al., J. Biol. Chem. 276 (47) :44003-44011 (2001) .
Other Product Names
TP53-regulating kinase, Atypical serine/threonine protein kinase TP53RK, EKC/KEOPS complex subunit TP53RK, 36--, Nori-2, p53-related protein kinase, TP53RK, C20orf64, PRPK
Tested Applications
WB, IHC-P
Protein ID
26398348
Physical Properties
Liquid

Related Products

CatalogName
62-982PRP4 Antibody
19-256PRPH Antibody
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
25-003L3MBTL2 Antibody
25-005C2orf28 Antibody
25-009HOXB3 Antibody
25-017OR13C5 Antibody
25-018CREBL1 Antibody

Alternative Products

CatalogName
MBS8308461-01Anti-PRPK Antibody
MBS9204654-01PRPK Antibody (Center)
AMM07355G-01PRPK Antibody (Center) [AMM07355G]
NBP1-69166Rabbit Polyclonal PRPK Antibody
SL19406R-01Rabbit Anti-PRPK antibody
OAAB17464-400ULPRPK Antibody - middle region
TA382739PRPK (TP53RK) Rabbit Polyclonal Antibody
MBS9227537-01PRPK Antibody (Center) Blocking Peptide
H00112858-M06Mouse Monoclonal PRPK Antibody (2E8)
NBP2-99394HRabbit Polyclonal PRPK Antibody [HRP]

Popular Products