RPS6KB2 Antibody

• Background:

  RPS6KB2 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B. Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.

• NCBI Gene ID:

  6199

• Swiss Prot:

  Q9UBS0

• Accession Number:

  Q9UBS0

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  This RPS6KB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-272 amino acids from the Central region of human RPS6KB2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Neuroscience, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  53 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  RPS6KB2

• NCBI Official Name:

  Ribosomal protein S6 kinase beta-2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26) :16899-16903 (2002) .

• Background Reference 02:

  Lee-Fruman, K.K., et al., Oncogene 18 (36) :5108-5114 (1999) .

• Background Reference 03:

  Saitoh, M., et al., Biochem. Biophys. Res. Commun. 253 (2) :470-476 (1998) .

• Background Reference 04:

  Gout, I., et al., J. Biol. Chem. 273 (46) :30061-30064 (1998) .

• Other Product Names:

  Ribosomal protein S6 kinase beta-2, S6K-beta-2, S6K2, 70 kDa ribosomal protein S6 kinase 2, P70S6K2, p70-S6K 2, S6 kinase-related kinase, SRK, Serine/threonine-protein kinase 14B, p70 ribosomal S6 kinase beta, S6K-beta, p70 S6 kinase beta, p70 S6K-beta, p70 S6KB, p70-beta, RPS6KB2, STK14B

• Tested Applications:

  WB

• Protein ID:

  296434560

• Physical Properties:

  Liquid