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CGKI Antibody

CAT: 0223-63-329Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-329Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
NCBI Gene ID
5592
Swiss Prot
Q13976
Accession Number
Q13976
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This cGKI (cGKI beta) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 629-660 amino acids from the C-terminal region of human cGKI beta.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
76 kDa
Fragment
Rabbit Ig
Symbol
PRKG1
NCBI Official Name
CGMP-dependent protein kinase 1
NCBI Organism
Homo sapiens
Background Reference 01
Orstavik, S., et al., Genomics 42 (2) :311-318 (1997) .
Background Reference 02
Tamura, N., et al., Hypertension 27 (3 Pt 2), 552-557 (1996) .
Other Product Names
CGMP-dependent protein kinase 1, cGK 1, cGK1, cGMP-dependent protein kinase I, cGKI, PRKG1, PRKG1B, PRKGR1A, PRKGR1B
Tested Applications
WB, IHC-P
Protein ID
6225588
Physical Properties
Liquid

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