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MST3 Antibody

CAT: 0223-63-290Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-290Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952) -binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000 [PubMed 10644707]) .[supplied by OMIM]
NCBI Gene ID
8428
Swiss Prot
Q9Y6E0
Accession Number
Q9Y6E0
Host
Rabbit
Reactivity
Human
Immunogen
This MST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-374 amino acids from the C-terminal region of human MST3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
49 kDa
Fragment
Rabbit Ig
Symbol
STK24
NCBI Official Name
Serine/threonine-protein kinase 24
NCBI Organism
Homo sapiens
Background Reference 01
Huang, C.Y., et al., J. Biol. Chem. 277 (37) :34367-34374 (2002) .
Background Reference 02
Christian, S.L., et al., Genomics 79 (5) :635-656 (2002) .
Background Reference 03
Zhou, T.H., et al., J. Biol. Chem. 275 (4) :2513-2519 (2000) .
Background Reference 04
Schinkmann, K., et al., J. Biol. Chem. 272 (45) :28695-28703 (1997) .
Other Product Names
Serine/threonine-protein kinase 24, Mammalian STE20-like protein kinase 3, MST-3, STE20-like kinase MST3, Serine/threonine-protein kinase 24 36 kDa subunit, Mammalian STE20-like protein kinase 3 N-terminal, MST3/N, Serine/threonine-protein kinase 24 12 kDa subunit, Mammalian STE20-like protein kinase 3 C-terminal, MST3/C, STK24, MST3, STK3
Tested Applications
WB, IHC-P
Protein ID
13626607
Physical Properties
Liquid

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