MST3 Antibody

• Background:

  The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952) -binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000 [PubMed 10644707]) .[supplied by OMIM]

• NCBI Gene ID:

  8428

• Swiss Prot:

  Q9Y6E0

• Accession Number:

  Q9Y6E0

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-374 amino acids from the C-terminal region of human MST3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  49 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  STK24

• NCBI Official Name:

  Serine/threonine-protein kinase 24

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Huang, C.Y., et al., J. Biol. Chem. 277 (37) :34367-34374 (2002) .

• Background Reference 02:

  Christian, S.L., et al., Genomics 79 (5) :635-656 (2002) .

• Background Reference 03:

  Zhou, T.H., et al., J. Biol. Chem. 275 (4) :2513-2519 (2000) .

• Background Reference 04:

  Schinkmann, K., et al., J. Biol. Chem. 272 (45) :28695-28703 (1997) .

• Other Product Names:

  Serine/threonine-protein kinase 24, Mammalian STE20-like protein kinase 3, MST-3, STE20-like kinase MST3, Serine/threonine-protein kinase 24 36 kDa subunit, Mammalian STE20-like protein kinase 3 N-terminal, MST3/N, Serine/threonine-protein kinase 24 12 kDa subunit, Mammalian STE20-like protein kinase 3 C-terminal, MST3/C, STK24, MST3, STK3

• Tested Applications:

  WB, IHC-P

• Protein ID:

  13626607

• Physical Properties:

  Liquid