ACHE Antibody

• Background:

  Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. The Protein is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits.

• NCBI Gene ID:

  43

• Swiss Prot:

  P22303

• Accession Number:

  P22303

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ACHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the N-terminal region of human ACHE.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Guinea Pig

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  68 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ACHE

• NCBI Official Name:

  Acetylcholinesterase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Liang, D., FEBS J. 276 (1), 94-108 (2009)

• Background Reference 02:

  Scacchi, R., Am. J. Med. Genet.Neuropsychiatr. Genet. (2008)

• Other Product Names:

  Acetylcholinesterase, AChE, ACHE

• Tested Applications:

  WB, IHC-P, IF, Flow

• Protein ID:

  113037

• Physical Properties:

  Liquid