Cyclin C Antibody

• Background:

  CCNC is a member of the cyclin family of proteins. This protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II.

• NCBI Gene ID:

  892

• Swiss Prot:

  P24863

• Accession Number:

  P24863

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This Cyclin C (CCNC) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-249 amino acids from the C-terminal region of human Cyclin C (CCNC) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Rat, Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  33 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CCNC

• NCBI Official Name:

  Cyclin-C

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Katona, R.L., Acta. Biol. Hung. 58 (1), 133-137 (2007)

• Background Reference 02:

  Ohata, N., Int. J. Mol. Med. 18 (6), 1153-1158 (2006)

• Background Reference 03:

  Sinkkonen, L., Nucleic Acids Res. 33 (8), 2440-2451 (2005)

• Other Product Names:

  Cyclin-C, SRB11 homolog, hSRB11, CCNC

• Tested Applications:

  WB

• Protein ID:

  166214910

• Physical Properties:

  Liquid