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BCHE Antibody

CAT: 0223-63-222Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-222Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mutant proteins of BCHE are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
NCBI Gene ID
590
Swiss Prot
P06276
Accession Number
P06276
Host
Rabbit
Reactivity
Human
Immunogen
This BCHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-415 amino acids from the Central region of human BCHE.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
68 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
BCHE
NCBI Official Name
Cholinesterase
NCBI Organism
Homo sapiens
Background Reference 01
Primo-Parmo S.L., Bartels C.F.Am. J. Hum. Genet. 58:52-64 (1996)
Background Reference 02
Primo-Parmo S.L., Lightstone H.Pharmacogenetics 7:27-34 (1997)
Background Reference 03
Yen T., Nightingale B.N.Clin. Chem. 49:1297-1308 (2003)
Other Product Names
Cholinesterase, Acylcholine acylhydrolase, Butyrylcholine esterase, Choline esterase II, Pseudocholinesterase, BCHE, CHE1
Tested Applications
WB
Protein ID
116353
Physical Properties
Liquid

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