TESK2 Antibody

• Background:

  TESK2 is a dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. TESK2 phosphorylates cofilin at Ser-3. It may play an important role in spermatogenesis. This nuclear enzyme is thought to be activated by autophosphorylation on Ser-219. Expression is predominantly in testis and prostate, with highest concentrations in nongerminal Sertoli cells.

• NCBI Gene ID:

  10420

• Swiss Prot:

  Q96S53

• Accession Number:

  Q96S53

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This TESK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-240 amino acids from the Central region of human TESK2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  64 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  TESK2

• NCBI Official Name:

  Dual specificity testis-specific protein kinase 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Toshima, J., J. Biol. Chem. 276 (33), 31449-31458 (2001)

• Background Reference 02:

  Rosok, O., Genomics 61 (1), 44-54 (1999)

• Other Product Names:

  Dual specificity testis-specific protein kinase 2, Testicular protein kinase 2, TESK2

• Tested Applications:

  WB, IHC-P

• Protein ID:

  25009462

• Physical Properties:

  Liquid