NTF3 Antibody

• Background:

  NTF3 is a member of the neurotrophin family that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.

• NCBI Gene ID:

  4908

• Swiss Prot:

  P20783

• Accession Number:

  P20783

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NTF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-151 amino acids from the Central region of human NTF3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Pig, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  29 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  NTF3

• NCBI Official Name:

  Neurotrophin-3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hossain, W.A., J. Neurosci. Res. 86 (11), 2376-2391 (2008)

• Background Reference 02:

  Mercader, J.M., Hum. Mol. Genet. 17 (9), 1234-1244 (2008)

• Background Reference 03:

  Kalcheim, C., Proc. Natl. Acad. Sci. U.S.A. 89 (5), 1661-1665 (1992)

• Other Product Names:

  Neurotrophin-3, NT-3, HDNF, Nerve growth factor 2, NGF-2, Neurotrophic factor, NTF3

• Tested Applications:

  WB, IHC-P

• Protein ID:

  128581

• Physical Properties:

  Liquid