STYK1 Antibody

• Background:

  STYK1, a probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways. It is widely expressed; highly expressed in brain, placenta and prostate. STYK1 is expressed in tumor cells such as hepatoma cells LO2, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K562, but not in other tumor cells such as epidermoid carcinoma.

• NCBI Gene ID:

  55359

• Swiss Prot:

  Q6J9G0

• Accession Number:

  Q6J9G0

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This STYK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-64 amino acids from the N-terminal region of human STYK1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  48 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  STYK1

• NCBI Official Name:

  Tyrosine-protein kinase STYK1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ye, X., et al., Mol. Biol. Rep. 30 (2) :91-96 (2003) .

• Other Product Names:

  Tyrosine-protein kinase STYK1, Novel oncogene with kinase domain, Protein PK-unique, Serine/threonine/tyrosine kinase 1, STYK1, NOK

• Tested Applications:

  WB

• Protein ID:

  317373546

• Physical Properties:

  Liquid