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ILK Antibody

CAT: 0223-63-101Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-101Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.
NCBI Gene ID
3611
Swiss Prot
Q13418
Accession Number
Q13418
Host
Rabbit
Reactivity
Human
Immunogen
This ILK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from human ILK.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Symbol
ILK
NCBI Official Name
Integrin-linked protein kinase
NCBI Organism
Homo sapiens
Background Reference 01
Li, Y., et al., J. Clin. Invest. 112 (4) :503-516 (2003) .
Background Reference 02
Troussard, A.A., et al., J. Biol. Chem. 278 (25) :22374-22378 (2003) .
Background Reference 03
Marotta, A., et al., Br. J. Cancer 88 (11) :1755-1762 (2003) .
Background Reference 04
Cordes, N., et al., Br. J. Cancer 88 (9) :1470-1479 (2003) .
Other Product Names
Integrin-linked protein kinase, 59 kDa serine/threonine-protein kinase, ILK-1, ILK-2, p59ILK, ILK, ILK1, ILK2
Tested Applications
WB, IHC-P
Protein ID
9973397
Physical Properties
Liquid

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