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NAB2 Antibody

CAT: 0223-63-078Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-078Size:400 µL
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Background
NAB2 is a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by this protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex.
NCBI Gene ID
4665
Swiss Prot
Q15742
Accession Number
Q15742
Host
Rabbit
Reactivity
Human
Immunogen
This NAB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human NAB2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
57 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NAB2
NCBI Official Name
NGFI-A-binding protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Srinivasan, R., J. Biol. Chem. 281 (22), 15129-15137 (2006)
Background Reference 02
Kumbrink, J., J. Biol. Chem. 280 (52), 42785-42793 (2005)
Background Reference 03
Lucerna, M., J. Biol. Chem. 278 (13), 11433-11440 (2003)
Other Product Names
NGFI-A-binding protein 2, EGR-1-binding protein 2, Melanoma-associated delayed early response protein, Protein MADER, NAB2, MADER
Tested Applications
WB
Protein ID
12643729
Physical Properties
Liquid

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