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PCSK2 Antibody

CAT: 0223-63-051Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-051Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PCSK2 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This protein is a proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. The protein is also known to cleave proopiomelanocortin, proenkephalin, prodynorphin and proluteinizing-hormone-releasing hormone.
NCBI Gene ID
5126
Swiss Prot
P16519
Accession Number
P16519
Host
Rabbit
Reactivity
Human
Immunogen
This PCSK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-346 amino acids from the Central region of human PCSK2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
71 kDa
Fragment
Rabbit Ig
Symbol
PCSK2
NCBI Official Name
Neuroendocrine convertase 2
NCBI Organism
Homo sapiens
Background Reference 01
Leak, T.S., Keene, K.L. Mol. Genet. Metab. 92 (1-2), 145-150 (2007)
Background Reference 02
Shen, X., Li, Q.L. Am. J. Physiol. Endocrinol. Metab. 288 (1), E236-E245 (2005)
Background Reference 03
Tzimas, G.N., Chevet, E. BMC Cancer 5, 149 (2005)
Background Reference 04
Seidah, N.G., Mattei, M.G. Genomics 11 (1), 103-107 (1991)
Other Product Names
Neuroendocrine convertase 2, NEC 2, KEX2-like endoprotease 2, Prohormone convertase 2, Proprotein convertase 2, PC2, PCSK2, NEC2
Tested Applications
WB, IHC-P, Flow
Protein ID
13124785
Physical Properties
Liquid

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