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LUM Antibody

CAT: 0223-63-034Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-034Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
LUM is a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, this protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. The protein is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.
NCBI Gene ID
4060
Swiss Prot
P51884
Accession Number
P51884
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This LUM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-91 amino acids from the N-terminal region of human LUM.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
38 kDa
Fragment
Rabbit Ig
Symbol
LUM
NCBI Official Name
Lumican
NCBI Organism
Homo sapiens
Background Reference 01
Wang, P., Li, S. Invest. Ophthalmol. Vis. Sci. 50 (4), 1546-1551 (2009)
Background Reference 02
Matsuda, Y., Yamamoto, T. Int. J. Oncol. 33 (6), 1177-1185 (2008)
Background Reference 03
Kelemen, L.E., Couch, F.J. Breast Cancer Res. 10 (6), R98 (2008)
Other Product Names
Lumican, Keratan sulfate proteoglycan lumican, KSPG lumican, LUM, LDC, SLRR2D
Tested Applications
WB, IHC-P, Flow
Protein ID
20141464
Physical Properties
Liquid

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