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CSF1R Antibody

CAT: 0223-63-033Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-033Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases.
NCBI Gene ID
1436
Swiss Prot
P07333
Accession Number
P07333
Host
Rabbit
Reactivity
Human
Immunogen
This CSF1R antibody is generated from rabbits immunized with CSF1R recombinant protein.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
108 kDa
Fragment
Rabbit Ig
Symbol
CSF1R
NCBI Official Name
Macrophage colony-stimulating factor 1 receptor
NCBI Organism
Homo sapiens
Background Reference 01
Guey, L.T., et.al., Eur. Urol. 57 (2), 283-292 (2010)
Background Reference 02
Wooten, E.C., et.al., PLoS ONE (1), E8830 (2010)
Background Reference 03
Hosgood, H.D. III, et.al., Respir Med 103 (12), 1866-1870 (2009)
Other Product Names
Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, CD115, CSF1R, FMS
Tested Applications
WB, IF, Flow
Protein ID
547770
Physical Properties
Liquid

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