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RAC1 Antibody

CAT: 0223-63-008Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-008Size:400 µL
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Background
RAC1 is a GTPase belonging to the RAS superfamily of small GTP-binding proteins. It is a pleiotropic regulator of many cellular processes, including the cell cycle, cell-cell adhesion, motility (through the actin network), and of epithelial differentiation (proposed to be necessary for maintaining epidermal stem cells) .
NCBI Gene ID
5879
Swiss Prot
P63000
Accession Number
P63000
Host
Rabbit
Reactivity
Human, Rat
Immunogen
This RAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-78 amino acids from human RAC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, C. Elegans, Chicken, Drosophila, Monkey, Mouse, Pig
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
21 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
RAC1
NCBI Official Name
Ras-related C3 botulinum toxin substrate 1
NCBI Organism
Homo sapiens
Background Reference 01
Wang, T., Neurosci. Lett. 437 (2), 71-75 (2008)
Background Reference 02
Gorshkova, I., J. Biol. Chem. 283 (17), 11794-11806 (2008)
Background Reference 03
Simeone-Penney, M.C., Am. J. Physiol. Lung Cell Mol. Physiol. 294 (4), L698-L704 (2008)
Other Product Names
Ras-related C3 botulinum toxin substrate 1, Cell migration-inducing gene 5 protein, Ras-like protein TC25, p21-Rac1, RAC1, TC25
Tested Applications
WB
Protein ID
51702787
Physical Properties
Liquid

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