RAC1 Antibody

• Background:

  RAC1 is a GTPase belonging to the RAS superfamily of small GTP-binding proteins. It is a pleiotropic regulator of many cellular processes, including the cell cycle, cell-cell adhesion, motility (through the actin network), and of epithelial differentiation (proposed to be necessary for maintaining epidermal stem cells) .

• NCBI Gene ID:

  5879

• Swiss Prot:

  P63000

• Accession Number:

  P63000

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  This RAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-78 amino acids from human RAC1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Immunology, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, C. Elegans, Chicken, Drosophila, Monkey, Mouse, Pig

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  21 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:2000

• Symbol:

  RAC1

• NCBI Official Name:

  Ras-related C3 botulinum toxin substrate 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wang, T., Neurosci. Lett. 437 (2), 71-75 (2008)

• Background Reference 02:

  Gorshkova, I., J. Biol. Chem. 283 (17), 11794-11806 (2008)

• Background Reference 03:

  Simeone-Penney, M.C., Am. J. Physiol. Lung Cell Mol. Physiol. 294 (4), L698-L704 (2008)

• Other Product Names:

  Ras-related C3 botulinum toxin substrate 1, Cell migration-inducing gene 5 protein, Ras-like protein TC25, p21-Rac1, RAC1, TC25

• Tested Applications:

  WB

• Protein ID:

  51702787

• Physical Properties:

  Liquid