BBS4 Antibody

• Background:

  BBS4 contains tetratricopeptide repeats (TPR), similar to O-linked N-acetyglucosamine transferase. Mutations in the gene encoding this protein have been observed in patients with Bardet-Biedl syndrome type 4. BBS4 may play a role in pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation.

• NCBI Gene ID:

  585

• Swiss Prot:

  Q96RK4

• Accession Number:

  Q96RK4

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This BBS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-369 amino acids from the Central region of human BBS4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Neuroscience

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  58 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  BBS4

• NCBI Official Name:

  Bardet-Biedl syndrome 4 protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Nachury, M.V., Cell 129 (6), 1201-1213 (2007)

• Background Reference 02:

  Ye, X., DNA Seq. 15 (3), 213-218 (2004)

• Background Reference 03:

  Kim, J.C., Nat. Genet. 36 (5), 462-470 (2004)

• Other Product Names:

  Bardet-Biedl syndrome 4 protein, BBS4

• Tested Applications:

  WB

• Protein ID:

  160359000

• Physical Properties:

  Liquid