BBS2 Antibody

• Background :

  This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with seven other BBS proteins.

• NCBI Gene ID :

  583

• Swiss Prot :

  Q9BXC9

• Host :

  Rabbit

• Reactivity :

  Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-96 of human BBS2 (NP_114091.3) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Cell Cycle, Neuroscience

• Purification :

  Affinity purification

• Positive Control :

  Mouse testis

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 100kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  BBS2

• Positive Control 2 :

  Mouse liver

• Positive Control 3 :

  Mouse kidney

• Positive Control 4 :

  Rat liver

• Positive Control 5 :

  Rat brain

• Positive Control 6 :

  Rat lung

• NCBI Official Name :

  Bardet-Biedl syndrome 2

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  BBS, RP74, Bardet-Biedl syndrome 2 protein

• Tested Applications :

  WB

• Physical Properties :

  Liquid