MEN1 Antibody

• Background:

  Menin (MEN1), a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known.

• NCBI Gene ID:

  4221

• Swiss Prot:

  O00255

• Accession Number:

  O00255

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MEN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-144 amino acids from human MEN1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  68 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  MEN1

• NCBI Official Name:

  Menin

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hashimoto, M., Int. J. Oncol. 33 (2), 333-340 (2008)

• Background Reference 02:

  Vidal, A., Eur Acad Dermatol Venereol 22 (7), 835-838 (2008)

• Background Reference 03:

  Pieterman, C.R., Clin. Endocrinol. (Oxf) (2008)

• Other Product Names:

  Menin, MEN1, SCG2

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid