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CEACAM Antibody

CAT: 0223-62-855Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-855Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CEACAM is a member of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. The protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.
NCBI Gene ID
634
Swiss Prot
P13688
Accession Number
P13688
Host
Rabbit
Reactivity
Human
Immunogen
This CEACAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-77 amino acids from the N-terminal region of human CEACAM.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
58 kDa
Fragment
Rabbit Ig
Symbol
CEACAM1
NCBI Official Name
Carcinoembryonic antigen-related cell adhesion molecule 1
NCBI Organism
Homo sapiens
Background Reference 01
Gambichler, T., Am. J. Clin. Pathol. 131 (6), 782-787 (2009)
Background Reference 02
Li, C., Exp. Cell Res. 315 (7), 1225-1233 (2009)
Background Reference 03
Nouvion, A.L., Med Sci (Paris) 25 (3), 247-252 (2009)
Other Product Names
Carcinoembryonic antigen-related cell adhesion molecule 1, Biliary glycoprotein 1, BGP-1, CD66a, CEACAM1, BGP, BGP1
Tested Applications
WB, IHC-P, Flow
Protein ID
399116
Physical Properties
Liquid

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