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CEACAM7 Antibody

CAT: 0223-58-984Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-984Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CEA-related cell adhesion molecule 7 (CEACAM7, CGM2) belongs to the carcinoembryonic antigen (CEA) family. It encodes a glycosyl phosphatidyl inositol (GPI) -linked glycoprotein which is only found on the apical surface of highly differentiated epithelial cells adult colon and on a small epithelial cell population in pancreatic ducts. CEACAM7 expression is completely lost upon malignant transformation already in hyperplastic polyps and early adenomas as well as in adenocarcinomas of the colon. Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by one immunoglobulin constantlike A domain.
NCBI Gene ID
1087
Swiss Prot
Q14002
Accession Number
Q14002
Host
Rabbit
Reactivity
Human
Immunogen
This CEACAM7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-140 amino acids from the Central region of human CEACAM7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
29 kDa
Fragment
Rabbit Ig
Symbol
CEACAM7
NCBI Official Name
Carcinoembryonic antigen-related cell adhesion molecule 7
NCBI Organism
Homo sapiens
Background Reference 01
Messick, C.A., et al. Surgery 147 (5) :713-719 (2010)
Background Reference 02
Douard, R., et al. Surgery 139 (4) :556-562 (2006)
Background Reference 03
Zhang, Z., et al. Protein Sci. 13 (10) :2819-2824 (2004)
Background Reference 04
Grimwood, J., et al. Nature 428 (6982) :529-535 (2004)
Other Product Names
Carcinoembryonic antigen-related cell adhesion molecule 7, Carcinoembryonic antigen CGM2, CEACAM7, CGM2
Tested Applications
WB, IHC-P
Protein ID
5921734
Physical Properties
Liquid

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