CEACAM3 Antibody

CAT: 0223-57-311Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-311Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
NCBI Gene ID
1084
Swiss Prot
P40198
Accession Number
P40198
Host
Rabbit
Reactivity
Human
Immunogen
This CEACAM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the C-terminal region of human CEACAM3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
27 kDa
Fragment
Rabbit Ig
Symbol
CEACAM3
NCBI Official Name
Carcinoembryonic antigen-related cell adhesion molecule 3
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Tsavaris, N., et al.Chemother 21 (6) :673-680 (2009)
Background Reference 03
Skubitz, K.M., et al.Transl Med 6, 78 (2008) :
Background Reference 04
Stern-Ginossar, N., et al. J. Immunol. 179 (7) :4424-4434 (2007)
Other Product Names
Carcinoembryonic antigen-related cell adhesion molecule 3, Carcinoembryonic antigen CGM1, CD66d, CEACAM3, CD66D, CGM1
Tested Applications
WB, IHC-P
Protein ID
218511974
Physical Properties
Liquid

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