CP Antibody

• Background:

  CP is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe (II) transferrin to Fe (III) transferrin. Mutations in this protein cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities.

• NCBI Gene ID:

  1356

• Swiss Prot:

  P00450

• Accession Number:

  P00450

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This CP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-151 amino acids from the N-terminal region of human CP.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  122 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CP

• NCBI Official Name:

  Ceruloplasmin

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Park, Y., Lee, I.S. Arch. Pharm. Res. 32 (5), 693-698 (2009)

• Background Reference 02:

  Altamura, C., Squitti, R. Stroke 40 (4), 1282-1288 (2009)

• Background Reference 03:

  Squitti, R., Quattrocchi, C.C. Prion (1), 23-27 (2008)

• Other Product Names:

  Ceruloplasmin, Ferroxidase, CP

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  116117

• Physical Properties:

  Liquid