CA5B Antibody

• Background:

  CA5B belongs a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. This protein is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. The protein has a wider tissue distribution than CA VA, which is restricted to the liver.

• NCBI Gene ID:

  11238

• Swiss Prot:

  Q9Y2D0

• Accession Number:

  Q9Y2D0

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This CA5B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-283 amino acids from the C-terminal region of human CA5B.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  36 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CA5B

• NCBI Official Name:

  Carbonic anhydrase 5B, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Vullo, D., Nishimori, I. Bioorg. Med. Chem. Lett. 17 (5), 1336-1340 (2007)

• Background Reference 02:

  Shah, G.N. Proc. Natl. Acad. Sci. U.S.A. 97 (4), 1677-1682 (2000)

• Background Reference 03:

  Fujikawa-Adachi, K. J. Biol. Chem. 274 (30), 21228-21233 (1999)

• Other Product Names:

  Carbonic anhydrase 5B, mitochondrial, Carbonate dehydratase VB, Carbonic anhydrase VB, CA-VB, CA5B

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  8928041

• Physical Properties:

  Liquid