CA2 Antibody

• Background:

  CA2 is one of several (at least 7) isozymes of carbonic anhydrase. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis.

• NCBI Gene ID:

  760

• Swiss Prot:

  P00918

• Accession Number:

  P00918

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This CA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-83 amino acids from the N-terminal region of human CA2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  29 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CA2

• NCBI Official Name:

  Carbonic anhydrase 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Sultana, R., et al. Antioxid. Redox Signal. 12 (3) :327-336 (2010)

• Background Reference 02:

  Fisher, S.Z., et al. Biochemistry 49 (3) :415-421 (2010)

• Background Reference 03:

  Avvaru, B.S., et al. Biochemistry 49 (2) :249-251 (2010)

• Background Reference 04:

  Maupin, C.M., et al. Biochemistry 48 (33) :7996-8005 (2009)

• Other Product Names:

  Carbonic anhydrase 2, Carbonate dehydratase II, Carbonic anhydrase C, CAC, Carbonic anhydrase II, CA-II, CA2

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid