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MYT1 Antibody

CAT: 0223-62-719Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-719Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported. Transcript Variant: This variant (1) encodes the longer isoform (1) .
NCBI Gene ID
9088
Swiss Prot
Q99640
Accession Number
Q99640
Host
Rabbit
Reactivity
Human
Immunogen
This MYT1 (PKMYT1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-482 amino acids from the C-terminal region of human MYT1 (PKMYT1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
55 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PKMYT1
NCBI Official Name
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
NCBI Organism
Homo sapiens
Background Reference 01
Dai, X., et al., J. Invest. Dermatol. 122 (6) :1356-1364 (2004) .
Background Reference 02
Nakajima, H., et al., J. Biol. Chem. 278 (28) :25277-25280 (2003) .
Background Reference 03
Passer, B.J., et al., Proc. Natl. Acad. Sci. U.S.A. 100 (5) :2284-2289 (2003) .
Background Reference 04
Okumura, E., et al., Nat. Cell Biol. 4 (2) :111-116 (2002) .
Other Product Names
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, Myt1 kinase, PKMYT1, MYT1
Tested Applications
WB
Protein ID
55976573
Physical Properties
Liquid

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