PIM3 Antibody

• Background:

  PIM3 is a memberof the Ser/Thr protein kinase family that may be involved in cell cycle progression and anti-apoptosis process. This protein has been implicated in proliferation of human hepatoma cell lines. PIM3 is widely expressed, with the exception of no expression observed in colon, thymus, and small intestine. PIM3 is expressed in human hepatoma cell lines but not in normal liver tissues.

• NCBI Gene ID:

  415116

• Swiss Prot:

  Q86V86

• Accession Number:

  Q86V86

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This PIM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-288 amino acids from the C-terminal region of human PIM3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  36 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PIM3

• NCBI Official Name:

  Serine/threonine-protein kinase pim-3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Mikkers, H., et al., Mol. Cell. Biol. 24 (13) :6104-6115 (2004) . Eichmann, A., et al., Oncogene 19 (9) :1215-1224 (2000) .

• Other Product Names:

  Serine/threonine-protein kinase pim-3, PIM3

• Tested Applications:

  WB, IHC-P

• Protein ID:

  215274221

• Physical Properties:

  Liquid